In the early years of the Republic of China, a young man named He Changsheng followed his grandfather from a young age to travel around and practice medicine to save people. He learned many skills. After his grandfather passed away, he and Fa Xiao'er Hu Yifa ventured into Shanghai and opened a small pharmacyTo practice medicine for the people. Until one day, while He and Hu were taking care of the shop, a woman dressed in Miao attire, Ah Man, came to him and demanded that He Changsheng fulfill his promise by repaying his father's debts to his son. The inexplicable He Changsheng andAman has a dispute. Just as the two were arguing, a man named He Renjian appeared with a team of foreign mercenaries to besiege the medical clinic